SARS-CoV-2 Airborne Neutralization Test

PlasmaGuard PRO™ Technology neutralizes tested envelope virus SARS-CoV-2 in real-world conditions for central HVAC systems.

PlasmaGuard technology demonstrated a 97.51% total neutralization of airborne SARS-CoV-2 in 29 minutes*.

PlasmaGuard technology neutralizes tested airborne virus SARS-CoV-2 in real-world conditions for a typical HVAC system configuration.

In vitro study performed by Innovative Bioanalysis proved PlasmaGuard’s ability to effectively inactivates SARS-CoV-2 in the air.*


Test the efficacy of PlasmaGuard PRO, powered by Purifi Labs, tehnology against aerosolized SARS-CoV-2 in real-world HVAC system test conditions.


Innovative Bioanalysis used a large, BSL-3 certified biosafety room to simulate realistic conditions within a commercial building or residential property.

PlasmaGuard technology was duct-mounted to the supply side of a real-world HVAC fan system, as recommended by the manufacturer for proper installation, supplying approximately 170 CFM of air into the room.

The HVAC fan system, contained entirely within the biosafety room, consisted of an air handler fan box connected to 32 feet of metal ductwork, with two diffusers positioned in similar interval distances to a typical indoor environment with a central HVAC system.

Test conditions represented an active mechanical system and indoor environment through a “Hot Start” scenario where the PlasmaGuard product and HVAC fan system were activated 15 minutes before introducing the pathogen into the environment.

Millions of micro-size SARS-CoV-2 viral aerosols were then aerosolized into the air through a central nebulization system, located at 5’ high, to simulate real-world human expulsion and behavior. The viral aerosol particles ranged in size between 0.8 micron and 1.4 micron, thereby representing real-world aerosol sizes that could be expelled by humans, remain airborne for extended periods of time, and fit within the size range of respirable particles.1 Four low speed mixing fans, operating at approximately 100 FPM, were located in each corner of the room to provide homogenous viral distribution and to represent human indoor walking speeds with intermittent frequency of movement.

Four equidistant bio sampling ports extended 24” down from the ceiling, into the “breathing zone”, along the centerline of the biosafety room, to simulate real-world human breathing locations throughout the room.


Air sampling was taken at four different time points, 3 minutes, 7 minutes, 14 minutes, and 29 minutes of elapsed exposure time. One static control and one airflow control were completed for each time point, and one viral challenge for each time point was conducted using the same methodology.

1 Thoracic and respirable particle definitions for human health risk assessment, J.Brown et al. Particle and Fibre Toxicology,2013, 10:12, content/10/1/12, 8977-10-12.pdf

*EnvironmentalTest Conditions: 1,280 cu. ft. biosafety room, 73°-77° F, 41%-45% RH, 170 CFM, and 8 ACH. There is currently no universal solution for preventing coronavirus infections. PlasmaGuard encourages following hygiene guidelines in the manner suggested by government authorities. To view complete test reports, visit our TestReport page:

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